Citagenix PentOs OI Max 1cc 100% Allograft Inductive collagen matrix

Description

PentOS OI™ Max | 100% Allograft Hydratable Inductive Matrix
Create your customized osteoinductive graft by combining PentOS OI™ Max, a 100% allograft Inductive Collagen Matrix (ICM) with your choice of blood, BMA, PRP, I-PRF or simply saline to form a moldable graft that is:

• Cell friendly
• Independent laboratory in vitro studies show to be able to maintain between 96% and 116% cell viability after 72 hours

PentOS OI™ Max is an osteoinductive matrix – not diluted by any carriers.
Proven to form bone. Every time. It’s that simple!

All PentOS OI™ allografts must demonstrate all five elements of bone formation before they are released for use.  

1. New bone
New bone is the final step in the maturation of the product.

2. Bone marrow
The presence of bone marrow indicates the ability of the product to differentiate into osteoblasts, chondrocytes, cartilage and new bone.

3. Osteocytes
Osteocytes are derived from osteoblasts, or bone forming cells, and are essentially osteoblasts surrounded by the products they secreted.

4. Cartilage
Cartilage is replaced by bone during ossification in the higher vertebrates. It is indicative that the bone formation is forthcoming.

5. Chondrocyte
A Chondrocyte is a unique cell type in articular cartilage tissue and is essential for cartilage formation and functionality. It arises from mesenchymal stem cells.

Features & benefits

• Mixed graft can be extruded through a syringe
• Demonstrated Osteoinductivity
  – up to 40x native BMP vs the BMP-2 control
  – each lot histologically demonstrates all 5 elements of bone formation
• pH balanced – non cytotoxic
• Shown to form bone post-sterilization in-vivo
• Resists copious irrigation
• 5 year shelf life at ambient storage